Mabhuthi has worked extensively in the United Kingdom with the National Health Service (NHS) helping this organization to streamline its business processes to meet the needs of the health sector in the UK. He has worked as a Business Analyst and Project Manager in a number of projects that helped to integrate IT systems within NHS with private sector health care partners such as Prudential Health, Partners in Care and Netcare. He was responsible for driving an initiative to streamline business process and ensuring that NHS benefited through the effective use of technology to ensure a better service to patients.

Mabhuthi boosts over 5 years experience in the UK healthcare sector. Prior to emigrating to the UK, Mabhuthi worked with Telkom SA Limited in their network operations centre as a project manager based in Pretoria.